KFC/MSRM Methods of Study of Reaction Mechanisms

Lecturer: Taťjana Nevěčná
Lecture: 2 hours/week
Credits: 2
Winter semester
Form of course completion: exam

• The Importace of Chemical Kinetics and the reaction mechanism
• The experimental Study of the Reaction rate
• The techniques for monitoring reaction progress in  gas phase. Modern experimental techniques.
• The methods for determination of the reaction rate. Determination of the reaction products and reaction intermediate
• The reaction conditions on the reaction rate. Determination of the kinetic equation.
• Bodenstein approximation of the quasi-steady-state. Consecutive reaction. Pre-equilibrium.
• Determination of the activation parameters of the chemical reaction
• Study of the catalysis. Acid-base catalysis. General acid-base catalysis and specific acid-base catalysis.
• Primary and secundary kinetic isotope effect. Kinetic isotope effect of the solvent.
• Enzyme catalysis
• The medium effect on the chemical reaction. Effect of the ionic strength on the reaction rate.
• The classification of the solvents and the solvent effects on the reaction rates. Empiric and semi-empiric parameters of the solvent polarity
• The reaction in very strong acid and very strong basic solvent.
• Linear free energy relationships.