BOT/RBROA Radiobiology

Lecturer: Vladan Ondřej
Lecture: 2 hours/week
Credits: 5
Winter semester
Form of course completion: exam

The important part of course will be focused on the organization of cell nucleus, DNA damage and repair in consequence to radiation. The course brings also an overview on radiation protection and legislation of protection in Czech republic.

• Introduction to composition of matter, fundamentals of physics, physical values
• Types of radiation, interactions of direct and non-direct ionizing radiation, radioisotopes
• Biological impact of ionizing radiation, deterministic and stochastic effects
• Organization of cell nucleus
• Interaction of radiation with DNA, DNA repair
• Effect of radiation on genome organization and stability
• Cytotoxicology of ionizing radiation
• Sources of ionizing radiation
• Basic aims and principals of radiation protection
• Legislation of radiation protection, nuclear law