P1527 Biology – Experimental Biology

Field of study guarantor: Prof. Ing. Miroslav Strnad, CSC.,DSc.

Guarantor of study: Laboratory of Growth Regulators

Field of study:

The aim of the doctoral study programme is training highly qualified scientific workers in the field of Experimental Biology. The students will acquire information about new findings in the area of Experimental Biology, Molecular and Cell Biology, Genetic, Microbiology, Plant Physiology, Pharmacology, Biology, Biochemistry, and Organic and Analytical Chemistry during the study programme in the form of lectures and consultations.  The Ph.D. students will improve their spoken and written English to be able to communicate within the scientific community, to write publications as well as give talks at international conferences. The core of the programme is based on experiments conducted under the supervision of experienced and highly qualified university lecturers and scientists from the Laboratory of Growth Regulators (LGR). The students will also be involved in the ongoing projects of the LGR research teams in the areas of Experimental Biology, Plant Physiology, Medicinal Chemistry, Pharmacology, Toxicology, Biochemistry, Molecular and Cell Biology, and Genetic. Leading-edge methods now used in Experimental Biology, Molecular and Cell Biology, Biochemistry and Genetics will be incorporated into the training.  

"Experimental Biology" is an independent biological discipline that studies biological processes at the molecular and cellular level, in particular using the most current experimental approaches, methods and technologies and the analyses of these processes. It includes the most progressively developing areas of biological and medical chemistry, bioanalysis, experimental biology, biotechnology and biomedicine. Graduates are trained for independent highly specialised work at a methodologically high quality level using the most up-to date instruments. Students are prepared both for independent scientific research work and independent scientific organizational activities

"Experimental Biology" includes new rapidly developing area of ​​biology focused on processes at the submicroscopic and microscopic level. Students acquire the necessary information about the biological, biochemical and biophysical processes at the molecular and cellular level, their interdependence, connection with the structuring of biological objects and their functional significance in the context of a multicellular organism, especially human. The study focuses on recent findings in experimental biology and biomedicine and their applications, new processes in DNA cloning, gene technology, genetic manipulation at the molecular level in plants and animals, on  submicroscopic methods of investigation, immunochemical and immunological methods for visualizing cellular structure, to genomics, proteomics and metabolomics, as well as on the medical aspects of biology. Major attention will be paid to biomedicine in the study of physiological and molecular-biological principles of human diseases. The main emphasis will be on understanding the principles and mechanisms of diseases (pathophysiology) and the related development of drugs (pharmacology) directed at molecular targets in pathological cells.

Graduate profile:

Graduates will gain a wide ranging and in-depth theoretical knowledge and as well, practical skills in all fields of experimental biology. They will deal,  in particular studies,  with the structure of (bio)molecules and their synthesis, analysis of biological materials, study of the relations between the structure of biomolecules and their biological activities, the molecular biology of genes and their expression in model organisms, the molecular nature of the interaction of plant and animal organisms and stressors, study of the structure of organisms at the cellular level and the interaction of organisms with xenobiotics. In all these areas, the Laboratory of Growth Regulators (LRR) has key partnerships, which allows doctoral students to study part of the problemas in specialized institutions in the Czech Republic and abroad. Experimental approaches are combined with synthetic approaches, analytical, genetic, biochemical, pharmacological, cellular and molecular. Significantly developing the study of pharmacological and medical issues, especially the development of drugs that are studied in collaboration with partners around the world. Bioinformatics and use of all biological and chemical databases is an integral part of the study. Students will be able in practice to apply the latest scientific findings in the field of Experimental Biology and related fields - genetics, molecular and cell biology, plant physiology, biochemistry and pharmacology, and others; will be able to independently plan research activities in a competitive environment grant schemes with a critical evaluation of the results, including statistical analysis. Graduates will control a wide range of modern experiments on molecular and cellular level, including techniques of instrumental analysis of biological samples; will be able to use and navigate the modern information technologies; will be able to acquire and process the latest scientific information from the world of electronic databases. Control the collection and processing of data in line wiring devices to test the validity of models and prepare their own graphically and substantively valuable presentations. The study will be conducted so that the graduate was maximally adaptable and able to navigate in the new trends in the field, which will bring the advancing time. Graduates can work in other academic career at universities, as workers state and private research laboratories in the Czech Republic and abroad. They can successfully perform tasks in laboratories focusing on human and veterinary medicine, pharmacy, agriculture, biotechnology and environmental protection fields. They will have the makings of managers and organizational staff research teams.

Information about application form

Thesis topics for J.L. Fischer scholarship